TBC1D23 抗体 (Internal Region)
Quick Overview for TBC1D23 抗体 (Internal Region) (ABIN6265479)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- TBC1D23 Antibody detects endogenous levels of total TBC1D23.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human TBC1D23, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-TBC1 Domain Family, Member 23 (TBC1D23) (AA 510-605) antibody
TBC1D23 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 23 (TBC1D23) (AA 250-600) antibodyTBC1D23 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 23 (TBC1D23) (C-Term) antibodyTBC1D23 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))
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别名
- TBC1D23
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背景
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Description: Putative Rab GTPase-activating protein which plays a role in vesicular trafficking (PubMed:28823707). Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles (PubMed:29084197). Plays a role in brain development, including in cortical neuron positioning (By similarity). May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth (By similarity). May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS) challenge (By similarity).
Gene: TBC1D23
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分子量
- 78 kDa
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基因ID
- 55773
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UniProt
- Q9NUY8
抗原
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