Syntaxin 17 抗体 (C-Term)
Quick Overview for Syntaxin 17 抗体 (C-Term) (ABIN6265405)
抗原
See all Syntaxin 17 (STX17) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Syntaxin 17 Antibody detects endogenous levels of total Syntaxin 17.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Syntaxin 17, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Syntaxin 17 (STX17) (AA 1-130) antibody
STX17 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 17 (STX17) (AA 1-30), (N-Term) antibodySTX17 适用: 人 WB 宿主: 兔 Polyclonal RB32919 unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Syntaxin 17 (STX17)
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别名
- STX17
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背景
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Description: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane (PubMed:23217709, PubMed:25686604). May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi (PubMed:21545355).
Gene: STX17
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分子量
- 33 kDa
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基因ID
- 55014
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UniProt
- P56962
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途径
- Synaptic Vesicle Exocytosis
抗原
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