SUPT4H 抗体 (C-Term)
Quick Overview for SUPT4H 抗体 (C-Term) (ABIN6265266)
抗原
See all SUPT4H (SUPT4H1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- SPT4H Antibody detects endogenous levels of total SPT4H.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human SPT4H, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Suppressor of Ty 4 Homolog 1 (SUPT4H1) (AA 18-117) antibody
SUPT4H1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G4 unconjugated
anti-Suppressor of Ty 4 Homolog 1 (SUPT4H1) (AA 1-117) antibodySUPT4H1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Ty 4 Homolog 1 (SUPT4H1) (AA 18-117) antibodySUPT4H1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Suppressor of Ty 4 Homolog 1 (SUPT4H1) (AA 57-106) antibodySUPT4H1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Ty 4 Homolog 1 (SUPT4H1) antibodySUPT4H1 适用: 人 DB 宿主: 小鼠 Monoclonal 3079C1a unconjugated
anti-Suppressor of Ty 4 Homolog 1 (SUPT4H1) (C-Term) antibodySUPT4H1 适用: 人, 小鼠, 大鼠, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Ty 4 Homolog 1 (SUPT4H1) (Middle Region) antibodySUPT4H1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- SUPT4H (SUPT4H1) (Suppressor of Ty 4 Homolog 1 (SUPT4H1))
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别名
- SUPT4H1
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背景
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Description: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme. Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites. DSIF can also positively regulate transcriptional elongation and is required for the efficient activation of transcriptional elongation by the HIV-1 nuclear transcriptional activator, Tat. DSIF acts to suppress transcriptional pausing in transcripts derived from the HIV-1 LTR and blocks premature release of HIV-1 transcripts at terminator sequences.
Gene: SUPT4H1
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分子量
- 13 kDa
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基因ID
- 6827
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UniProt
- P63272
抗原
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