SOCS2 抗体
Quick Overview for SOCS2 抗体 (ABIN6265216)
抗原
See all SOCS2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- SOCS2 Antibody detects endogenous levels of total SOCS2
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human SOCS2
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:1000-3000 IF/ICC 1:200-1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
-
有效期
- 12 months
-
-
- SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))
-
别名
- SOCS2
-
背景
-
Description: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Gene: SOCS2
-
分子量
- 23 kDa
-
基因ID
- 8835
-
UniProt
- O14508
-
途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus
抗原
-