SNX17 抗体 (N-Term)
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北京 101111
Quick Overview for SNX17 抗体 (N-Term) (ABIN6265212)
抗原
See all SNX17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- SNX17 Antibody detects endogenous levels of total SNX17.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human SNX17, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Sorting Nexin 17 (SNX17) (AA 280-457) antibody
SNX17 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 17 (SNX17) (AA 1-470) antibodySNX17 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sorting Nexin 17 (SNX17) (AA 1-470) antibodySNX17 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A3 unconjugated
anti-Sorting Nexin 17 (SNX17) (AA 1-195) antibodySNX17 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- SNX17 (Sorting Nexin 17 (SNX17))
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别名
- SNX17
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背景
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Description: Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).
Gene: SNX17
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分子量
- 50 kDa
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基因ID
- 9784
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UniProt
- Q15036
抗原
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