SLIT2 抗体 (Internal Region)
Quick Overview for SLIT2 抗体 (Internal Region) (ABIN6265158)
抗原
See all SLIT2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- SLIT2 Antibody detects endogenous levels of total SLIT2.
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预测反应
- Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human SLIT2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Slit Homolog 2 (Drosophila) (SLIT2) (AA 1416-1528) antibody
SLIT2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 2 (Drosophila) (SLIT2) (AA 664-777) antibodySLIT2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 2 (Drosophila) (SLIT2) antibodySLIT2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 2 (Drosophila) (SLIT2) (AA 1160-1333) antibodySLIT2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 2 (Drosophila) (SLIT2) antibodySLIT2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Slit Homolog 2 (Drosophila) (SLIT2) (AA 451-550) antibodySLIT2 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 2 (Drosophila) (SLIT2) (AA 1361-1460) antibodySLIT2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Slit Homolog 2 (Drosophila) (SLIT2) (AA 1416-1528) antibody (Biotin)SLIT2 适用: 人 WB 宿主: 兔 Polyclonal Biotin
anti-Slit Homolog 2 (Drosophila) (SLIT2) (AA 1416-1528) antibody (FITC)SLIT2 适用: 人 WB 宿主: 兔 Polyclonal FITC
anti-Slit Homolog 2 (Drosophila) (SLIT2) (AA 1330-1529) antibodySLIT2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))
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别名
- SLIT2
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背景
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Description: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.
Gene: SLIT2
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分子量
- 169 kDa
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基因ID
- 9353
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UniProt
- O94813
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途径
- Regulation of Actin Filament Polymerization, Regulation of Cell Size, Smooth Muscle Cell Migration
抗原
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