SIRT5 抗体 (Internal Region)
Quick Overview for SIRT5 抗体 (Internal Region) (ABIN6265094)
抗原
See all SIRT5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- SIRT5 Antibody detects endogenous levels of total SIRT5.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human SIRT5, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Sirtuin 5 (SIRT5) (AA 37-310) antibody
SIRT5 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) antibodySIRT5 适用: 人, 大鼠 WB, IHC, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Sirtuin 5 (SIRT5) (AA 120-170) antibodySIRT5 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 179-228) antibodySIRT5 适用: 人, 小鼠, Cow, 山羊, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (C-Term) antibodySIRT5 适用: 人, 山羊, Pig, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (Middle Region) antibodySIRT5 适用: 人, 小鼠, Cow, 山羊, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 37-310) antibodySIRT5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 60-212) antibodySIRT5 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 184-233) antibodySIRT5 适用: 人, 小鼠, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 1-310) antibodySIRT5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- SIRT5 (Sirtuin 5 (SIRT5))
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别名
- SIRT5
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背景
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Description: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins (PubMed:21908771, PubMed:22076378, PubMed:24703693, PubMed:29180469). Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting (PubMed:22076378, PubMed:24703693). Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species (PubMed:24140062). Activates SHMT2 by mediating its desuccinylation (PubMed:29180469). Modulates ketogenesis through the desuccinylation and activation of HMGCS2 (By similarity). Has weak NAD-dependent protein deacetylase activity, however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as UOX.
Gene: SIRT5
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分子量
- 34 kDa
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基因ID
- 23408
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UniProt
- Q9NXA8
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途径
- SARS-CoV-2 Protein Interactome
抗原
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