SIRT5 抗体 (Internal Region)
Our Local Distributor
北京 101111
Quick Overview for SIRT5 抗体 (Internal Region) (ABIN6265094)
抗原
See all SIRT5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
特异性
- SIRT5 Antibody detects endogenous levels of total SIRT5.
-
预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human SIRT5, corresponding to a region within the internal amino acids.
-
亚型
- IgG
-
-
anti-Sirtuin 5 (SIRT5) (AA 37-310) antibody
SIRT5 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) antibodySIRT5 适用: 人, 大鼠 WB, IHC, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Sirtuin 5 (SIRT5) (AA 120-170) antibodySIRT5 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 179-228) antibodySIRT5 适用: 人, 小鼠, Cow, 山羊, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (C-Term) antibodySIRT5 适用: 人, 山羊, Pig, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (Middle Region) antibodySIRT5 适用: 人, 小鼠, Cow, 山羊, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 37-310) antibodySIRT5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 60-212) antibodySIRT5 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 1-310) antibodySIRT5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 184-233) antibodySIRT5 适用: 人, 小鼠, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- SIRT5 (Sirtuin 5 (SIRT5))
-
别名
- SIRT5
-
背景
-
Description: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins (PubMed:21908771, PubMed:22076378, PubMed:24703693, PubMed:29180469). Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting (PubMed:22076378, PubMed:24703693). Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species (PubMed:24140062). Activates SHMT2 by mediating its desuccinylation (PubMed:29180469). Modulates ketogenesis through the desuccinylation and activation of HMGCS2 (By similarity). Has weak NAD-dependent protein deacetylase activity, however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as UOX.
Gene: SIRT5
-
分子量
- 34 kDa
-
基因ID
- 23408
-
UniProt
- Q9NXA8
-
途径
- SARS-CoV-2 Protein Interactome
抗原
-
