SIRT3 抗体 (C-Term)
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北京 101111
Quick Overview for SIRT3 抗体 (C-Term) (ABIN6265092)
抗原
See all SIRT3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- SIRT3 Antibody detects endogenous levels of total SIRT3.
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预测反应
- Sheep,Rabbit
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human SIRT3, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Sirtuin 3 (SIRT3) (C-Term) antibody
SIRT3 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 250-279), (C-Term) antibodySIRT3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB01967 unconjugated
anti-Sirtuin 3 (SIRT3) (AA 126-399) antibodySIRT3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 127-303) antibodySIRT3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 155-290) antibodySIRT3 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 6B2A1 unconjugated
anti-Sirtuin 3 (SIRT3) (AA 304-334), (C-Term) antibodySIRT3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB25945 unconjugated
anti-Sirtuin 3 (SIRT3) (AA 304-334) antibodySIRT3 适用: 人, 小鼠, Hamster WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 250-279) antibodySIRT3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 5-257) antibodySIRT3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 20-130) antibodySIRT3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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: "Single-walled carbon nanohorn aggregates promotes mitochondrial dysfunction-induced apoptosis in hepatoblastoma cells by targeting SIRT3." in: International journal of oncology, Vol. 53, Issue 3, pp. 1129-1137, (2018) (PubMed).
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: "Single-walled carbon nanohorn aggregates promotes mitochondrial dysfunction-induced apoptosis in hepatoblastoma cells by targeting SIRT3." in: International journal of oncology, Vol. 53, Issue 3, pp. 1129-1137, (2018) (PubMed).
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- SIRT3 (Sirtuin 3 (SIRT3))
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别名
- SIRT3
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背景
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Description: NAD-dependent protein deacetylase (PubMed:12186850, PubMed:12374852, PubMed:16788062, PubMed:18680753, PubMed:18794531, PubMed:23283301, PubMed:24121500, PubMed:24252090, PubMed:19535340). Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues (PubMed:12186850, PubMed:12374852, PubMed:16788062, PubMed:18680753, PubMed:18794531, PubMed:23283301, PubMed:24121500, PubMed:24252090). Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O (PubMed:16788062, PubMed:18680753, PubMed:24121500, PubMed:24252090, PubMed:19535340). Contributes to the regulation of the cellular energy metabolism (PubMed:24252090). Important for regulating tissue-specific ATP levels (PubMed:18794531). In response to metabolic stress, deacetylates transcription factor FOXO3 and recruits FOXO3 and mitochondrial RNA polymerase POLRMT to mtDNA to promote mtDNA transcription (PubMed:23283301).
Gene: SIRT3
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分子量
- 29 kDa
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基因ID
- 23410
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UniProt
- Q9NTG7
抗原
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