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SIRT3 抗体 (C-Term)

Name: SIRT3 抗体 (C-Term)
SKU: ABIN6265092
Availability: OutOfStock

This anti-SIRT3 antibody is a 兔多克隆 antibody detecting SIRT3 in WB, IHC, ELISA, ICC 和 IF. Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 1 publication.

Western blot analysis of SIRT3 expression in Mouse Heart lysate,The lane on the left is treated with the antigen-specific peptide. (SIRT3 抗体 (C-Term))

IF/ICC

ABIN6268681 at 1/100 staining Mouse testis tissue by IHC-P. (SIRT3 抗体 (C-Term))

IHC

3 images

(1 reference)

产品编号 ABIN6265092

发货至: 中国

Quick Overview for SIRT3 抗体 (C-Term) (ABIN6265092)

抗原

See all SIRT3 抗体

SIRT3 (Sirtuin 3 (SIRT3))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This SIRT3 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Discover our top product SIRT3 Primary Antibody

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C-Term

特异性

SIRT3 Antibody detects endogenous levels of total SIRT3.

预测反应

Sheep,Rabbit

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human SIRT3, corresponding to a region within C-terminal amino acids.

亚型

IgG
anti-Sirtuin 3 (SIRT3) (C-Term) antibody
SIRT3 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 3 (SIRT3) (AA 250-279), (C-Term) antibody
SIRT3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB01967 unconjugated

anti-Sirtuin 3 (SIRT3) (AA 126-399) antibody
SIRT3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 3 (SIRT3) (AA 127-303) antibody
SIRT3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 3 (SIRT3) (AA 155-290) antibody
SIRT3 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 6B2A1 unconjugated

anti-Sirtuin 3 (SIRT3) (AA 304-334), (C-Term) antibody
SIRT3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB25945 unconjugated

anti-Sirtuin 3 (SIRT3) (AA 304-334) antibody
SIRT3 适用: 人, 小鼠, Hamster WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 3 (SIRT3) (AA 250-279) antibody
SIRT3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 3 (SIRT3) (AA 5-257) antibody
SIRT3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 3 (SIRT3) (AA 20-130) antibody
SIRT3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
Li, Chen, Yang, He, He, Xia, Zhang, Xiang: "Single-walled carbon nanohorn aggregates promotes mitochondrial dysfunction-induced apoptosis in hepatoblastoma cells by targeting SIRT3." in: International journal of oncology, Vol. 53, Issue 3, pp. 1129-1137, (2018) (PubMed).
抗原

SIRT3 (Sirtuin 3 (SIRT3))

别名

SIRT3

背景

Description: NAD-dependent protein deacetylase (PubMed:12186850, PubMed:12374852, PubMed:16788062, PubMed:18680753, PubMed:18794531, PubMed:23283301, PubMed:24121500, PubMed:24252090, PubMed:19535340). Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues (PubMed:12186850, PubMed:12374852, PubMed:16788062, PubMed:18680753, PubMed:18794531, PubMed:23283301, PubMed:24121500, PubMed:24252090). Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O (PubMed:16788062, PubMed:18680753, PubMed:24121500, PubMed:24252090, PubMed:19535340). Contributes to the regulation of the cellular energy metabolism (PubMed:24252090). Important for regulating tissue-specific ATP levels (PubMed:18794531). In response to metabolic stress, deacetylates transcription factor FOXO3 and recruits FOXO3 and mitochondrial RNA polymerase POLRMT to mtDNA to promote mtDNA transcription (PubMed:23283301).
Gene: SIRT3

分子量

29 kDa

基因ID

23410

UniProt

Q9NTG7