SIAH2 抗体 (C-Term)
Quick Overview for SIAH2 抗体 (C-Term) (ABIN6265080)
抗原
See all SIAH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- SIAH2 Antibody detects endogenous levels of total SIAH2.
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预测反应
- Pig,Bovine,Sheep,Rabbit,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human SIAH2, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (AA 1-72) antibody
SIAH2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (AA 216-244) antibodySIAH2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22563 unconjugated
anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (C-Term) antibodySIAH2 适用: 人, 小鼠, 大鼠, 斑马鱼 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (C-Term) antibodySIAH2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (C-Term) antibodySIAH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (N-Term) antibodySIAH2 适用: 人, 小鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (AA 215-264) antibodySIAH2 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, Pig, 豚鼠, 马, 兔, 猴, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (Middle Region) antibodySIAH2 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (AA 1-100), (N-Term) antibodySIAH2 适用: 人, Pig IHC, FACS, IF, ICC 宿主: 小鼠 Monoclonal 24E6H3 unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- SIAH2 (Siah E3 Ubiquitin Protein Ligase 2 (SIAH2))
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别名
- SIAH2
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背景
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Description: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.
Gene: MEN1
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分子量
- 36 kDa
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基因ID
- 6478
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UniProt
- O43255
抗原
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