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- 抗原 See all SGTA 抗体
- SGTA (Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SGTA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- SGTA Antibody detects endogenous levels of total SGTA.
- 预测反应
- Pig,Zebrafish,Bovine,Sheep,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human SGTA, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product SGTA Primary Antibody
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anti-Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) (AA 42-123) antibody
SGTA 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 2E11 unconjugated
anti-Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) (AA 1-313) antibodySGTA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) (AA 1-313) antibodySGTA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) (Center) antibodySGTA 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) (AA 1-120) antibodySGTA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) (AA 84-97) antibodyVerified SGTA 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) antibodySGTA 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) antibodySGTA 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- SGTA (Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA))
- 别名
- SGTA (SGTA 产品)
- 别名
- sgta antibody, SGTA antibody, zgc:92462 antibody, SGT antibody, alphaSGT antibody, hSGT antibody, 5330427H01Rik antibody, AI194281 antibody, D10Ertd190e antibody, Sgt antibody, Stg antibody, small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha antibody, small glutamine rich tetratricopeptide repeat containing alpha antibody, small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta antibody, small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha L homeolog antibody, sgta antibody, SGTA antibody, sgtb antibody, sgta.L antibody, Sgta antibody
- 背景
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Description: Co-chaperone that binds misfolded and hydrophobic patches-containing client proteins in the cytosol. Mediates their targeting to the endoplasmic reticulum but also regulates their sorting to the proteasome when targeting fails (PubMed:28104892). Functions in tail-anchored/type II transmembrane proteins membrane insertion constituting with ASNA1 and the BAG6 complex a targeting module (PubMed:28104892). Probably functions upstream of the BAG6 complex and ASNA1, binding more rapidly the transmembrane domain of newly synthesized proteins (PubMed:28104892). It is also involved in the regulation of the endoplasmic reticulum-associated misfolded protein catabolic process via its interaction with BAG6: collaborates with the BAG6 complex to maintain hydrophobic substrates in non-ubiquitinated states (PubMed:23129660, PubMed:25179605). Competes with RNF126 for interaction with BAG6, preventing the ubiquitination of client proteins associated with the BAG6 complex (PubMed:27193484). Binds directly to HSC70 and HSP70 and regulates their ATPase activity (PubMed:18759457).
Gene: SGTA
- 分子量
- 34-37 kDa
- 基因ID
- 6449
- UniProt
- O43765
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