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SENP2 抗体

This anti-SENP2 antibody is a 兔 多克隆 antibody detecting SENP2 in WB, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6264984
发货至: 中国

Quick Overview for SENP2 抗体 (ABIN6264984)

抗原

See all SENP2 抗体
SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

适用

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人, 小鼠, 大鼠

宿主

  • 48
  • 7

克隆类型

  • 48
  • 7
多克隆

标记

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This SENP2 antibody is un-conjugated

应用范围

  • 45
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 特异性

    SENP2 Antibody detects endogenous levels of total SENP2

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human SENP2

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000 IF/ICC 1:200-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C.Stable for 12 months from date of receipt

    有效期

    12 months
  • 抗原

    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

    别名

    SENP2

    背景

    Description: Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB (PubMed:20194620).

    Gene: SENP2

    分子量

    68 kDa

    基因ID

    59343

    UniProt

    Q9HC62

    途径

    Chromatin Binding
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