SDCBP 抗体 (Internal Region)
Quick Overview for SDCBP 抗体 (Internal Region) (ABIN6264952)
抗原
See all SDCBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- SDCBP Antibody detects endogenous levels of total SDCBP.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human SDCBP, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 1-100) antibody
SDCBP 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 2C12 unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 1-298) antibodySDCBP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 21-228) antibodySDCBP 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 1-298) antibodySDCBP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) antibodySDCBP 适用: 人, 大鼠, 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) antibodySDCBP 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 1-30), (N-Term) antibodySDCBP 适用: 人 WB 宿主: 兔 Polyclonal RB42325 unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 101-150) antibodySDCBP 适用: 人, 大鼠, 小鼠, 犬, Pig, Cow, 马, 豚鼠, 兔, 小鸡, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 1-260) antibodySDCBP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) antibodySDCBP 适用: 人, 大鼠, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))
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别名
- SDCBP
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背景
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Description: Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis (PubMed:26291527). Positively regulates TGFB1-mediated SMAD2/3 activation and TGFB1-induced epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types. May increase TGFB1 signaling by enhancing cell-surface expression of TGFR1 by preventing the interaction between TGFR1 and CAV1 and subsequent CAV1-dependent internalization and degradation of TGFR1 (PubMed:25893292). In concert with SDC1/4 and PDCD6IP, regulates exosome biogenesis (PubMed:22660413). Regulates migration, growth, proliferation, and cell cycle progression in a variety of cancer types (PubMed:26539120). In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA) (PubMed:11498591). May also play a role in vesicular trafficking (PubMed:11179419). Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway (PubMed:10230395).
Gene: SDCBP
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分子量
- 32kDa
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基因ID
- 6386
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UniProt
- O00560
抗原
-
