SART3 抗体 (C-Term)
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北京 101111
Quick Overview for SART3 抗体 (C-Term) (ABIN6264927)
抗原
See all SART3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- SART3 Antibody detects endogenous levels of total SART3.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human SART3, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) (AA 664-963) antibody
SART3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) (N-Term) antibodySART3 适用: 人, 大鼠, 豚鼠, 犬, 马, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) antibodySART3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) (AA 1-129) antibodySART3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) (N-Term) antibodySART3 适用: 人, 豚鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) (AA 600-900) antibodySART3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) (C-Term) antibodyVerified SART3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) (C-Term) antibodySART3 适用: 人, 小鼠, 大鼠, 豚鼠, 犬, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) (AA 827-876) antibodySART3 适用: 人, 小鼠, 大鼠, 豚鼠, 犬, 马, Pig, Cow, 兔, 斑马鱼, 猴, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) (Middle Region) antibodySART3 适用: 人, 小鼠, 大鼠, 豚鼠, 犬, 马, Cow, 兔, 斑马鱼, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))
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别名
- SART3
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背景
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Description: U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation (PubMed:12032085). Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites (PubMed:14749385). May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. Recruits USP4 to ubiquitinated PRPF3 within the U4/U5/U6 tri-snRNP complex, promoting PRPF3 deubiquitination and thereby regulating the spliceosome U4/U5/U6 tri-snRNP spliceosomal complex disassembly (PubMed:20595234). May also recruit the deubiquitinase USP15 to histone H2B and mediate histone deubiquitination, thereby regulating gene expression and/or DNA repair (PubMed:24526689). May play a role in hematopoiesis probably through transcription regulation of specific genes including MYC (By similarity).
Gene: SART3
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分子量
- 110kDa
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基因ID
- 9733
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UniProt
- Q15020
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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