S100B 抗体 (C-Term)
Quick Overview for S100B 抗体 (C-Term) (ABIN6264909)
抗原
See all S100B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - C-Term
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特异性
 - S100B Antibody detects endogenous levels of total S100B.
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预测反应
 - Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
 - The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
 - A synthesized peptide derived from human S100B, corresponding to a region within C-terminal amino acids.
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亚型
 - IgG
 
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应用备注
 - WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 mg/mL
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缓冲液
 - Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
 - 12 months
 
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- S100B (S100 Calcium Binding Protein B (S100B))
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别名
 - S100B
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背景
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Description: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Gene: S100B
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分子量
 - 11kDa
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基因ID
 - 6285
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UniProt
 - P04271
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途径
 - Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
 
抗原
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