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S100B 抗体 (C-Term)

This anti-S100B antibody is a 兔 多克隆 antibody detecting S100B in WB, IHC 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6264909
发货至: 中国

Quick Overview for S100B 抗体 (C-Term) (ABIN6264909)

抗原

See all S100B 抗体
S100B (S100 Calcium Binding Protein B (S100B))

适用

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  • 1
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人, 大鼠, 小鼠

宿主

  • 137
  • 90
  • 10
  • 2
  • 2
  • 1

克隆类型

  • 126
  • 116
多克隆

标记

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  • 7
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  • 1
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This S100B antibody is un-conjugated

应用范围

  • 176
  • 126
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  • 49
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 45
    • 15
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    S100B Antibody detects endogenous levels of total S100B.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human S100B, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    S100B (S100 Calcium Binding Protein B (S100B))

    别名

    S100B

    背景

    Description: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

    Gene: S100B

    分子量

    11kDa

    基因ID

    6285

    UniProt

    P04271

    途径

    Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
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