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RRM2 抗体 (C-Term)

This anti-RRM2 antibody is a 兔 多克隆 antibody detecting RRM2 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6264868
发货至: 中国

Quick Overview for RRM2 抗体 (C-Term) (ABIN6264868)

抗原

See all RRM2 抗体
RRM2 (Ribonucleotide Reductase M2 (RRM2))

适用

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人, 小鼠, 大鼠

宿主

  • 52
  • 6

克隆类型

  • 43
  • 14
  • 1
多克隆

标记

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  • 1
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This RRM2 antibody is un-conjugated

应用范围

  • 40
  • 16
  • 13
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  • 7
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  • 4
  • 3
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  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    C-Term

    特异性

    RRM2 Antibody detects endogenous levels of total RRM2.

    预测反应

    Bovine,Horse,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human RRM2, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • Xia, Wang, Song, Meng, Huang, Huang: "Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 107, (2018) (PubMed).

  • 抗原

    RRM2 (Ribonucleotide Reductase M2 (RRM2))

    别名

    RRM2

    背景

    Description: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.

    Gene: RRM2

    分子量

    45kDa

    基因ID

    6241

    UniProt

    P31350

    途径

    Mitotic G1-G1/S Phases
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