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RRAGA 抗体 (C-Term)

This anti-RRAGA antibody is a 兔 多克隆 antibody detecting RRAGA in ELISA 和 WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6264863
发货至: 中国

Quick Overview for RRAGA 抗体 (C-Term) (ABIN6264863)

抗原

See all RRAGA 抗体
RRAGA (Ras-Related GTP Binding A (RRAGA))

适用

  • 27
  • 10
  • 10
  • 1
人, 小鼠, 大鼠

宿主

  • 27

克隆类型

  • 26
  • 1
多克隆

标记

  • 10
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RRAGA antibody is un-conjugated

应用范围

  • 14
  • 13
  • 11
  • 3
  • 3
  • 2
  • 2
  • 1
ELISA, Western Blotting (WB)
  • 抗原表位

    • 6
    • 2
    • 1
    • 1
    • 1
    C-Term

    特异性

    RRAGA Antibody detects endogenous levels of total RRAGA.

    预测反应

    Pig,Zebrafish,Bovine,Sheep,Rabbit,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human RRAGA, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    RRAGA (Ras-Related GTP Binding A (RRAGA))

    别名

    RRAGA

    背景

    Description: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

    Gene: RRAGA

    分子量

    37 kDa

    基因ID

    10670

    UniProt

    Q7L523
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