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RNF5 抗体 (C-Term)

This anti-RNF5 antibody is a 兔 多克隆 antibody detecting RNF5 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6264790
发货至: 中国
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Quick Overview for RNF5 抗体 (C-Term) (ABIN6264790)

抗原

See all RNF5 抗体
RNF5 (Ring Finger Protein 5, E3 Ubiquitin Protein Ligase (RNF5))

适用

  • 36
  • 12
  • 11
  • 3
  • 3
  • 3
  • 1
人, 小鼠, 大鼠

宿主

  • 36

克隆类型

  • 36
多克隆

标记

  • 19
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RNF5 antibody is un-conjugated

应用范围

  • 29
  • 17
  • 11
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 9
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    C-Term

    特异性

    RNF5 Antibody detects endogenous levels of total RNF5.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human RNF5, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    RNF5 (Ring Finger Protein 5, E3 Ubiquitin Protein Ligase (RNF5))

    别名

    RNF5

    背景

    Description: Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD, the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the 'Lys-48'-linked polyubiquitination of TMEM173 at 'Lys-150' leading to its proteasomal degradation, the ubiquitination occurs in mitochondria after viral transfection and regulates antiviral responses.

    Gene: RNF5

    分子量

    20 kDa

    基因ID

    6048

    UniProt

    Q99942
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