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RNF5 抗体 (C-Term)

This anti-RNF5 antibody (ABIN6264790) is a Rabbit Polyclonal antibody detecting RNF5 in WB, ELISA. Suitable for Human, Mouse, Rat.
产品编号 ABIN6264790
发货至: 中国

Quick Overview for RNF5 抗体 (C-Term) (ABIN6264790)

抗原

See all RNF5 抗体
RNF5 (Ring Finger Protein 5, E3 Ubiquitin Protein Ligase (RNF5))

适用

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人, 小鼠, 大鼠

宿主

  • 38

克隆类型

  • 38
多克隆

标记

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This RNF5 antibody is un-conjugated

应用范围

  • 31
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Western Blotting (WB), ELISA
  • 抗原表位

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    C-Term

    特异性

    RNF5 Antibody detects endogenous levels of total RNF5.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human RNF5, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    RNF5 (Ring Finger Protein 5, E3 Ubiquitin Protein Ligase (RNF5))

    别名

    RNF5

    背景

    Description: Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD, the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the 'Lys-48'-linked polyubiquitination of TMEM173 at 'Lys-150' leading to its proteasomal degradation, the ubiquitination occurs in mitochondria after viral transfection and regulates antiviral responses.

    Gene: RNF5

    分子量

    20 kDa

    基因ID

    6048

    UniProt

    Q99942
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