RIOK3 抗体 (Internal Region)
Quick Overview for RIOK3 抗体 (Internal Region) (ABIN6264759)
抗原
See all RIOK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- RIOK3 Antibody detects endogenous levels of total RIOK3.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human RIOK3, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-RRIO Kinase 3 (RIOK3) (AA 1-516) antibody
RIOK3 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4A12-1D2 unconjugated
anti-RRIO Kinase 3 (RIOK3) (AA 411-516) antibodyRIOK3 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3G11 unconjugated
anti-RRIO Kinase 3 (RIOK3) (AA 1-519) antibodyRIOK3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-RRIO Kinase 3 (RIOK3) (C-Term) antibodyRIOK3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 斑马鱼, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-RRIO Kinase 3 (RIOK3) antibodyRIOK3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-RRIO Kinase 3 (RIOK3) (AA 146-179) antibodyRIOK3 适用: 人 WB 宿主: 兔 Polyclonal RB49659 unconjugated
anti-RRIO Kinase 3 (RIOK3) (AA 1-519) antibodyRIOK3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-RRIO Kinase 3 (RIOK3) (AA 434-483) antibodyRIOK3 适用: 人, 小鼠, 大鼠, Cow, 猴, 豚鼠, 马, 兔, 斑马鱼, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-RRIO Kinase 3 (RIOK3) (AA 200-519) antibodyRIOK3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- RIOK3 (RRIO Kinase 3 (RIOK3))
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别名
- RIOK3
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背景
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Description: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. May act as an adapter protein essential for the recruitment of TBK1 to IRF3 (PubMed:24807708). Phosphorylates IFIH1 on 'Ser-828' interfering with IFIH1 filament assembly on long dsRNA and resulting in attenuated IFIH1-signaling (PubMed:25865883). Can inhibit CASP10 isoform 7-mediated activation of the NF-kappaB signaling pathway (PubMed:19557502). May play a role in the biogenesis of the 40S ribosomal subunit. Involved in the processing of 21S pre-rRNA to the mature 18S rRNA (PubMed:22418843).
Gene: RIOK3
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分子量
- 59 kDa
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基因ID
- 8780
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UniProt
- O14730
抗原
-
