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RIOK1 抗体 (C-Term)

This anti-RIOK1 antibody is a 兔 多克隆 antibody detecting RIOK1 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6264758
发货至: 中国

Quick Overview for RIOK1 抗体 (C-Term) (ABIN6264758)

抗原

See all RIOK1 抗体
RIOK1 (RIO Kinase 1 (RIOK1))

适用

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人, 小鼠, 大鼠

宿主

  • 32
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克隆类型

  • 33
  • 2
多克隆

标记

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This RIOK1 antibody is un-conjugated

应用范围

  • 31
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 7
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    • 3
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    C-Term

    特异性

    RIOK1 Antibody detects endogenous levels of total RIOK1.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human RIOK1, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    RIOK1 (RIO Kinase 1 (RIOK1))

    别名

    RIOK1

    背景

    Description: Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor (PubMed:22072790). The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit (By similarity). Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity). The catalytic activity regulates its dynamic association with the 40S subunit (By similarity). In addition to its role in ribosomal biogenesis acts as an adapter protein by recruiting NCL/nucleolin the to PRMT5 complex for its symmetrical methylation (PubMed:21081503).

    Gene: RIOK1

    分子量

    66 kDa

    基因ID

    83732

    UniProt

    Q9BRS2
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