ARHGAP24 抗体 (Internal Region)
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北京 101111
Quick Overview for ARHGAP24 抗体 (Internal Region) (ABIN6264735)
抗原
See all ARHGAP24 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- RHG24 Antibody detects endogenous levels of total RHG24.
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预测反应
- Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human RHG24, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-rho GTPase Activating Protein 24 (ARHGAP24) (AA 501-600) antibody
ARHGAP24 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-rho GTPase Activating Protein 24 (ARHGAP24) (AA 1-653) antibodyARHGAP24 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
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别名
- ARHGAP24
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背景
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Description: Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.
Gene: ARHGAP24
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分子量
- 84 kDa
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基因ID
- 83478
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UniProt
- Q8N264
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途径
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
抗原
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