REST 抗体 (C-Term)
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Quick Overview for REST 抗体 (C-Term) (ABIN6264701)
抗原
See all REST 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- REST Antibody detects endogenous levels of total REST.
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预测反应
- Horse,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human REST, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-RE1-Silencing Transcription Factor (REST) (AA 401-450) antibody
REST 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (Middle Region) antibodyREST 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) antibodyREST 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) antibodyREST 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB1200 unconjugated Recombinant Antibody
anti-RE1-Silencing Transcription Factor (REST) (AA 760-1060) antibodyREST 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (AA 250-350) antibodyREST 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) antibodyREST 适用: 人 WB 宿主: 小鼠 Monoclonal 25GB8545 unconjugated
anti-RE1-Silencing Transcription Factor (REST) (Internal Region) antibodyVerified REST 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (AA 972-1021) antibodyREST 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (AA 20-69) antibodyREST 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- REST (RE1-Silencing Transcription Factor (REST))
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别名
- REST
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背景
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Description: Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression.
Gene: REST
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分子量
- 121 kDa
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基因ID
- 5978
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UniProt
- Q13127
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途径
- Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
抗原
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