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RCC1 抗体 (N-Term)

This anti-RCC1 antibody is a 兔 多克隆 antibody detecting RCC1 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6264679
发货至: 中国

Quick Overview for RCC1 抗体 (N-Term) (ABIN6264679)

抗原

See all RCC1 抗体
RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

适用

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人, 小鼠, 大鼠

宿主

  • 60
  • 10
  • 2

克隆类型

  • 61
  • 11
多克隆

标记

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This RCC1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    N-Term

    特异性

    RCC1 Antibody detects endogenous levels of total RCC1.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human RCC1, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

    别名

    RCC1

    背景

    Description: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis (PubMed:1944575, PubMed:17435751, PubMed:20668449, PubMed:22215983, PubMed:11336674). Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis (PubMed:12194828, PubMed:17435751, PubMed:22215983). Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import (PubMed:22215983). Involved in the regulation of onset of chromosome condensation in the S phase (PubMed:3678831). Binds both to the nucleosomes and double-stranded DNA (PubMed:17435751, PubMed:18762580).

    Gene: RCC1

    分子量

    ?45 kDa

    基因ID

    1104

    UniProt

    P18754

    途径

    Chromatin Binding, Protein targeting to Nucleus
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