RASSF1 抗体 (Internal Region)
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北京 101111
Quick Overview for RASSF1 抗体 (Internal Region) (ABIN6264654)
抗原
See all RASSF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- RASSF1 Antibody detects endogenous levels of total RASSF1.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human RASSF1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 145-260) antibody
RASSF1 适用: 人, 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 101-340) antibodyRASSF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 1-340) antibodyRASSF1 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (Center) antibodyRASSF1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 1-340) antibodyRASSF1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 1-340), (Isoform A), (N-Term) antibodyRASSF1 适用: 人 WB, IF, EIA 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 23-145) antibodyRASSF1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 1-270) antibodyRASSF1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 201-250) antibodyRASSF1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 绵羊, 斑马鱼, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (C-Term) antibodyRASSF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
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别名
- RASSF1
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背景
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Description: Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Isoform A interacts with CDC20, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression. Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein. Isoform C has been shown not to perform these roles, no function has been identified for this isoform. Isoform A disrupts interactions among MDM2, DAXX and USP7, thus contributing to the efficient activation of TP53 by promoting MDM2 self-ubiquitination in cell-cycle checkpoint control in response to DNA damage.
Gene: RASSF1
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分子量
- 39kDa
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基因ID
- 11186
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UniProt
- Q9NS23
抗原
-
