Retinoic Acid Receptor alpha 抗体 (N-Term)
Quick Overview for Retinoic Acid Receptor alpha 抗体 (N-Term) (ABIN6264642)
抗原
See all Retinoic Acid Receptor alpha (RARA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Retinoic Acid Receptor alpha Antibody detects endogenous levels of total Retinoic Acid Receptor alpha.
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预测反应
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Retinoic Acid Receptor alpha, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Retinoic Acid Receptor, alpha (RARA) (AA 68-173) antibody
RARA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 315-424) antibodyRARA 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D2 unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 1-457) antibodyRARA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 237-459) antibodyRARA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 315-424) antibodyRARA 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1C10 unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 1-462) antibodyRARA 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2C9-1F8 unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 322-349), (C-Term) antibodyRARA 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB33783 unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (pSer77) antibodyRARA 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (C-Term) antibodyVerified RARA 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 315-424) antibodyRARA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C3 unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
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别名
- RARA
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背景
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Description: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (By similarity).
Gene: RARA
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分子量
- 51kDa
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基因ID
- 5914
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UniProt
- P10276
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins
抗原
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