rala 抗体 (C-Term)
Quick Overview for rala 抗体 (C-Term) (ABIN6264624)
抗原
See all rala 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- RALA Antibody detects endogenous levels of total RALA.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human RALA, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Ras-related Protein Ral-A (rala) (AA 1-206) antibody
rala 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C13 unconjugated
anti-Ras-related Protein Ral-A (rala) (AA 71-203) antibodyrala 适用: 人, 小鼠, 猴 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 4G8C7 unconjugated
anti-Ras-related Protein Ral-A (rala) (AA 71-203) antibodyrala 适用: 人, 小鼠, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4G8B11 unconjugated
anti-Ras-related Protein Ral-A (rala) antibodyrala 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras-related Protein Ral-A (rala) (Center) antibodyrala 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ras-related Protein Ral-A (rala) (AA 1-203) antibodyrala 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras-related Protein Ral-A (rala) (pSer194) antibodyrala 适用: 人 ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3E6 unconjugated
anti-Ras-related Protein Ral-A (rala) (AA 1-206) antibodyrala 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras-related Protein Ral-A (rala) (AA 1-206) antibodyrala 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ras-related Protein Ral-A (rala) (AA 71-120) antibodyrala 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼, 猴, 小鸡, Bat, Hamster, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- rala (Ras-related Protein Ral-A (rala))
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别名
- RALA
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背景
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Description: Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling (PubMed:20005108). Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells (PubMed:19306925). During mitosis, supports the stabilization and elongation of the intracellular bridge between dividing cells. Cooperates with EXOC2 to recruit other components of the exocyst to the early midbody (PubMed:18756269).
Gene: RALA
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分子量
- 24 kDa
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基因ID
- 5898
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UniProt
- P11233
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途径
- Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
抗原
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