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RAB35 抗体 (Internal Region)

This anti-RAB35 antibody is a 兔 多克隆 antibody detecting RAB35 in ELISA, WB, IHC, IF 和 ICC. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6264573
发货至: 中国

Quick Overview for RAB35 抗体 (Internal Region) (ABIN6264573)

抗原

See all RAB35 抗体
RAB35 (RAB35, Member RAS Oncogene Family (RAB35))

适用

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  • 2
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人, 大鼠, 小鼠

宿主

  • 54
  • 2
  • 2

克隆类型

  • 58
多克隆

标记

  • 26
  • 5
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  • 1
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This RAB35 antibody is un-conjugated

应用范围

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  • 22
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ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 16
    • 8
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    • 2
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    • 2
    • 1
    • 1
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    Internal Region

    特异性

    RAB35 Antibody detects endogenous levels of total RAB35.

    预测反应

    Pig,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human RAB35, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    RAB35 (RAB35, Member RAS Oncogene Family (RAB35))

    别名

    RAB35

    背景

    Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth. Together with TBC1D13 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane in adipocytes.

    Gene: RAB35

    分子量

    23 kDa

    基因ID

    11021

    UniProt

    Q15286
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