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RAB17 抗体 (Internal Region)

This anti-RAB17 antibody is a 兔 多克隆 antibody detecting RAB17 in WB, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6264559
发货至: 中国

Quick Overview for RAB17 抗体 (Internal Region) (ABIN6264559)

抗原

See all RAB17 抗体
RAB17 (RAB17, Member RAS Oncogene Family (RAB17))

适用

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人, 小鼠, 大鼠

宿主

  • 39
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  • 1

克隆类型

  • 40
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多克隆

标记

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This RAB17 antibody is un-conjugated

应用范围

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  • 18
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    Internal Region

    特异性

    RAB17 Antibody detects endogenous levels of total RAB17.

    预测反应

    Pig,Bovine,Sheep,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human RAB17, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    RAB17 (RAB17, Member RAS Oncogene Family (RAB17))

    别名

    RAB17

    背景

    Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking through apical recycling endosomes in a post-endocytic step of transcytosis. Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development (By similarity). May also play a role in cell migration.

    Gene: RAB17

    分子量

    23 kDa

    基因ID

    64284

    UniProt

    Q9H0T7
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