PSME3 抗体 (N-Term)
Quick Overview for PSME3 抗体 (N-Term) (ABIN6264495)
抗原
See all PSME3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- PSME3 Antibody detects endogenous levels of total PSME3.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human PSME3, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-PSME3 (PSME3) (AA 7-254) antibody
PSME3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) antibodyKO Validated PSME3 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (AA 2-252) antibodyPSME3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) antibodyPSME3 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (AA 1-254) antibodyPSME3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-PSME3 (PSME3) (C-Term) antibodyPSME3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (N-Term) antibodyPSME3 适用: 人, 大鼠, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (N-Term) antibodyPSME3 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (AA 48-97) antibodyPSME3 适用: 人, 大鼠, 小鼠, 犬, Pig, Cow, 豚鼠, 马, 兔, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (C-Term) antibodyPSME3 适用: 人, 大鼠, 小鼠, 犬, Pig, Cow, 豚鼠, 马, 兔, 斑马鱼, 小鸡, 非洲爪蟾, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- PSME3
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别名
- PSME3
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背景
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Description: Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation. Mediates CCAR2 and CHEK2-dependent SIRT1 inhibition (PubMed:25361978).
Gene: PSME3
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分子量
- 30kDa
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基因ID
- 10197
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UniProt
- P61289
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA
抗原
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