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DLG4 抗体 (C-Term)

This anti-DLG4 antibody is a 兔 多克隆 antibody detecting DLG4 in WB, IHC 和 ELISA. Suitable for 大鼠, 人 和 小鼠.
产品编号 ABIN6264460
发货至: 中国

Quick Overview for DLG4 抗体 (C-Term) (ABIN6264460)

抗原

See all DLG4 抗体
DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

适用

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大鼠, 人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This DLG4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    C-Term

    特异性

    PSD95 Antibody detects endogenous levels of total PSD95.

    预测反应

    Zebrafish,Bovine,Horse,Sheep,Rabbit

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human PSD95, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

    别名

    DLG4

    背景

    Description: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression.

    Gene: DLG4

    分子量

    105 kDa

    基因ID

    1742

    UniProt

    P78352

    途径

    Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity
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