PRC1 抗体 (Internal Region)
Quick Overview for PRC1 抗体 (Internal Region) (ABIN6264405)
抗原
See all PRC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- PRC1 Antibody detects endogenous levels of total PRC1.
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预测反应
- Pig,Horse,Sheep,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human PRC1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Protein Regulator of Cytokinesis 1 (PRC1) (AA 351-620) antibody
PRC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Regulator of Cytokinesis 1 (PRC1) (AA 1-620) antibodyPRC1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B10-1F9 unconjugated
anti-Protein Regulator of Cytokinesis 1 (PRC1) (pThr481) antibodyPRC1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Regulator of Cytokinesis 1 (PRC1) (AA 460-520) antibodyPRC1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Regulator of Cytokinesis 1 (PRC1) (AA 1-150) antibodyPRC1 适用: 人 WB 宿主: 小鼠 Monoclonal 6G2 unconjugated
anti-Protein Regulator of Cytokinesis 1 (PRC1) (Middle Region) antibodyPRC1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
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别名
- PRC1
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背景
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Description: Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).
Gene: PRC1
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分子量
- 72kDa
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基因ID
- 9055
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UniProt
- O43663
抗原
-
