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BPIFA1 抗体 (Internal Region)

This anti-BPIFA1 antibody is a 兔 多克隆 antibody detecting BPIFA1 in WB, ELISA 和 IHC. Suitable for 人 和 大鼠.
产品编号 ABIN6264311
发货至: 中国

Quick Overview for BPIFA1 抗体 (Internal Region) (ABIN6264311)

抗原

See all BPIFA1 抗体
BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))

适用

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人, 大鼠

宿主

  • 13
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  • 1

克隆类型

  • 14
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多克隆

标记

  • 18
This BPIFA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    Internal Region

    特异性

    PLUNC Antibody detects endogenous levels of total PLUNC.

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human PLUNC, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))

    别名

    BPIFA1

    背景

    Description: Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Binds bacterial lipopolysaccharide (LPS). Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants. May attract macrophages and neutrophils. May be associated with tumor progression.

    Gene: BPIFA1

    分子量

    27 kDa

    基因ID

    51297

    UniProt

    Q9NP55
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