PKM 抗体 (Internal Region)
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北京 101111
Quick Overview for PKM 抗体 (Internal Region) (ABIN6264260)
抗原
See all PKM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- PKM2 Antibody detects endogenous levels of total PKM2.
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预测反应
- Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human PKM2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Pyruvate Kinase M1/2 (PKM) (AA 11-221) antibody
PKM 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (AA 2-531) antibodyPKM 适用: 人 ELISA, WB, IHC, IF, IP, FACS 宿主: 小鼠 Monoclonal 6C3C7 unconjugated
anti-Pyruvate Kinase M1/2 (PKM) antibodyPKM 适用: 人 ELISA, WB, IHC, IF, IP, FACS 宿主: 兔 Monoclonal 7B2 unconjugated Recombinant Antibody
anti-Pyruvate Kinase M1/2 (PKM) (AA 11-221) antibodyPKM 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (AA 185-461) antibodyPKM 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (AA 2-192) antibodyPKM 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (pSer37) antibodyPKM 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) antibodyPKM 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (AA 1-531) antibodyPKM 适用: 人 ELISA, WB, IF, ICC 宿主: 小鼠 Monoclonal AT1B10 unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (pSer37) antibodyPKM 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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: "Diallyl Disulfide Inhibits Breast Cancer Stem Cell Progression and Glucose Metabolism by Targeting CD44/PKM2/AMPK Signaling." in: Current cancer drug targets, Vol. 18, Issue 6, pp. 592-599, (2018) (PubMed).
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: "Diallyl Disulfide Inhibits Breast Cancer Stem Cell Progression and Glucose Metabolism by Targeting CD44/PKM2/AMPK Signaling." in: Current cancer drug targets, Vol. 18, Issue 6, pp. 592-599, (2018) (PubMed).
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- PKM (Pyruvate Kinase M1/2 (PKM))
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别名
- PKM
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背景
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Description: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
Gene: PKM
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分子量
- 58 kDa
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基因ID
- 5315
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UniProt
- P14618
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途径
- Warburg Effect
抗原
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