PI3K p85/p55 抗体 (Internal Region)
(1 reference)Our Local Distributor
北京 101111
Quick Overview for PI3K p85/p55 抗体 (Internal Region) (ABIN6264193)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
原理
- PI3K p85/p55 Antibody
-
特异性
- PI3-kinase p85-alpha/gamma Antibody detects endogenous levels of total PI3-kinase p85-alpha/gamma
-
预测反应
- Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human PI3K p85p55, corresponding to a region within the internal amino acids.
-
亚型
- IgG
-
-
anti-Phosphoinositide 3 Kinase, p85/p55 (PI3K p85/p55) (pTyr199), (pTyr467) antibody
PI3K p85/p55 适用: 人, 小鼠, 大鼠, 猴, Pig IHC, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85/p55 (PI3K p85/p55) (pTyr199), (pTyr458), (pTyr467) antibodyPI3K p85/p55 适用: 人, 小鼠, 大鼠, 猴 IHC, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85/p55 (PI3K p85/p55) (pTyr199), (pTyr467) antibodyPI3K p85/p55 适用: 人, 小鼠, 大鼠, 猴 IHC, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85/p55 (PI3K p85/p55) (Internal Region) antibodyPI3K p85/p55 适用: 人, 小鼠 IHC, WB 宿主: 小鼠 Monoclonal AFfirm8126 unconjugated
-
-
应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
-
: "Biological functions of lung cancer cells are suppressed in co-culture with mesenchymal stem cells isolated from umbilical cord." in: Experimental and therapeutic medicine, Vol. 15, Issue 1, pp. 1076-1080, (2018) (PubMed).
-
-
- PI3K p85/p55 (Phosphoinositide 3 Kinase, p85/p55 (PI3K p85/p55))
-
别名
- PI3K p85/p55
-
背景
-
Description: Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling (PubMed:17626883, PubMed:19805105, PubMed:7518429). Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (PubMed:20348923).
Gene: PIK3R1
-
分子量
- 54,83kDa
-
基因ID
- 5295
-
UniProt
- P27986
抗原
-
