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PIK3R1 抗体 (C-Term)

Name: PIK3R1 抗体 (C-Term)
SKU: ABIN6264192
Availability: OutOfStock

This anti-PIK3R1 antibody is a 兔多克隆 antibody detecting PIK3R1 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 3+ publications.

Western blot analysis of PI3-kinase p85-alpha expression in COS7 whole cell lysates. (PIK3R1 抗体 (C-Term))

Western blot analysis of extracts from Hela, using PI3-kinase p85-alpha Antibody. (PIK3R1 抗体 (C-Term))

2 images

(3 references)

产品编号 ABIN6264192

发货至: 中国

Datasheet as PDF

Quick Overview for PIK3R1 抗体 (C-Term) (ABIN6264192)

抗原

See all PIK3R1 (PI3K p85a) 抗体

PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This PIK3R1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Discover our top product PI3K p85a Primary Antibody

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C-Term

特异性

PI3K p85 alpha Antibody detects endogenous levels of total PI3K p85 alpha.

预测反应

Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human PI3K p85 alpha, corresponding to a region within C-terminal amino acids.

亚型

IgG
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 1-454) antibody
PI3K p85a 适用: 人 WB, ELISA, IP, PLA 宿主: 小鼠 Monoclonal 3A10 unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (pTyr607) antibody
PI3K p85a 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 159-388) antibody
PI3K p85a 适用: 人, 小鼠 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 6G10 unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 501-600) antibody
PI3K p85a 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 1-30), (N-Term) antibody
PI3K p85a 适用: 人, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB11634 unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 159-388) antibody
PI3K p85a 适用: 人, 小鼠 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 15-180) antibody
PI3K p85a 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) antibody
PI3K p85a 适用: 小鼠, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 3B7 unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 1-424) antibody
PI3K p85a 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (pTyr368) antibody
PI3K p85a 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
Li, Xiong, Xu, Duan, Yang, Zhou, Tu: "miR-29a regulated ER-positive breast cancer cell growth and invasion and is involved in the insulin signaling pathway." in: Oncotarget, Vol. 8, Issue 20, pp. 32566-32575, (2018) (PubMed).

Liu, Geng, Zhang, Wang, Zhang, Duan, Zhang: "Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway." in: Marine drugs, Vol. 16, Issue 3, (2018) (PubMed).

Wang, Li, Chen, Yang: "Umbilical cord‑derived mesenchymal stem cells can inhibit the biological functions of melanoma A375 cells." in: Oncology reports, Vol. 40, Issue 1, pp. 511-517, (2018) (PubMed).
抗原

PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

别名

PIK3R1

背景

Description: Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling (PubMed:17626883, PubMed:19805105, PubMed:7518429). Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (PubMed:20348923).
Gene: PIK3R1

分子量

85 kDa

基因ID

5295

UniProt

P27986

途径

TCR Signaling, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, Warburg Effect