PIK3R2 抗体 (C-Term)
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北京 101111
Quick Overview for PIK3R2 抗体 (C-Term) (ABIN6264187)
抗原
See all PIK3R2 (PI3K p85b) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- PI 3 Kinase p85 beta Antibody detects endogenous levels of total PI 3 Kinase p85 beta.
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预测反应
- Pig,Zebrafish,Bovine,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human PI 3 Kinase p85 beta, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibody
PI3K p85b 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 1-60) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 75-125), (Regulatory Subunit) antibodyPI3K p85b 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠, Cow, 犬 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5210 unconjugated Recombinant Antibody
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 268-298), (C-Term) antibodyPI3K p85b 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1716 unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 445-474) antibodyPI3K p85b 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB13091 unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 1-30), (N-Term) antibodyPI3K p85b 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB11635 unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))
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别名
- PIK3R2
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背景
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Description: Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Indirectly regulates autophagy (PubMed:23604317). Promotes nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (By similarity).
Gene: PIK3R2
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分子量
- 82kDa
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基因ID
- 5296
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UniProt
- O00459
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途径
- VEGF Signaling, BCR Signaling
抗原
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