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PFN1 抗体 (C-Term)

This anti-PFN1 antibody is a 兔 多克隆 antibody detecting PFN1 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6264161
发货至: 中国

Quick Overview for PFN1 抗体 (C-Term) (ABIN6264161)

抗原

See all PFN1 抗体
PFN1 (Profilin 1 (PFN1))

适用

  • 61
  • 34
  • 32
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 71
  • 6
  • 1

克隆类型

  • 63
  • 15
多克隆

标记

  • 32
  • 10
  • 9
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
This PFN1 antibody is un-conjugated

应用范围

  • 43
  • 30
  • 19
  • 14
  • 14
  • 12
  • 8
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 14
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    Profilin 1 Antibody detects endogenous levels of total Profilin 1.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human Profilin 1, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    PFN1 (Profilin 1 (PFN1))

    别名

    PFN1

    背景

    Description: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.

    Gene: PFN1

    分子量

    15kDa

    基因ID

    5216

    UniProt

    P07737

    途径

    Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location
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