PDZK1 抗体 (C-Term)
Quick Overview for PDZK1 抗体 (C-Term) (ABIN6264124)
抗原
See all PDZK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- PDZK1 Antibody detects endogenous levels of total PDZK1.
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预测反应
- Bovine,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human PDZK1, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-PDZ Domain Containing 1 (PDZK1) (AA 1-519) antibody
PDZK1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1C3-2B11 unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (AA 1-520) antibodyPDZK1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1C3-2B11 unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (AA 1-519) antibodyPDZK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (AA 1-519) antibodyPDZK1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (N-Term) antibodyPDZK1 适用: 人, 小鼠, 犬, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (AA 80-129) antibodyPDZK1 适用: 人, 小鼠, 大鼠, 豚鼠, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (AA 1-260) antibodyPDZK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (N-Term) antibodyPDZK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (N-Term) antibodyPDZK1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (AA 196-224) antibodyPDZK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- PDZK1 (PDZ Domain Containing 1 (PDZK1))
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别名
- PDZK1
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背景
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Description: A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. Required for normal cell-surface expression of SCARB1. Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1. Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney. May be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).
Gene: PDZK1
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分子量
- 57kDa
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基因ID
- 5174
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UniProt
- Q5T2W1
抗原
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