p107 抗体 (C-Term)
Quick Overview for p107 抗体 (C-Term) (ABIN6263929)
抗原
See all p107 (RBL1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- P107 Antibody detects endogenous levels of total p107.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human p107, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 905-1014) antibody
RBL1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 1007-1035), (C-Term) antibodyRBL1 适用: 人 WB 宿主: 兔 Polyclonal RB40387 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 1-1014) antibodyRBL1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (pSer975) antibodyRBL1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7537 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (pSer975) antibodyRBL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 201-500) antibodyRBL1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 143-192) antibodyRBL1 适用: 人, 小鼠, Cow, 马, Pig, 犬, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 935-984) antibodyRBL1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 100-200) antibodyRBL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (N-Term) antibodyRBL1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))
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别名
- RBL1
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背景
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Description: Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor.
Gene: RBL1
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分子量
- 119 kDa
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基因ID
- 5933
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UniProt
- P28749
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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