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alpha KGDHC 抗体 (N-Term)

This anti-alpha KGDHC antibody is a 兔 多克隆 antibody detecting alpha KGDHC in WB, IHC, IF 和 ICC. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6263803
发货至: 中国

Quick Overview for alpha KGDHC 抗体 (N-Term) (ABIN6263803)

抗原

See all alpha KGDHC (alphaKGDHC) 抗体
alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))

适用

  • 30
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人, 大鼠, 小鼠

宿主

  • 29
  • 3

克隆类型

  • 29
  • 3
多克隆

标记

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This alpha KGDHC antibody is un-conjugated

应用范围

  • 28
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  • 7
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    N-Term

    特异性

    OGDH Antibody detects endogenous levels of total OGDH.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human OGDH, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))

    别名

    OGDH

    背景

    Description: 2-oxoglutarate dehydrogenase (E1) component of the 2-oxoglutarate dehydrogenase complex, which mediates the decarboxylation of alpha-ketoglutarate (PubMed:24495017). The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2 (PubMed:24495017). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion (PubMed:29211711). A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (PubMed:29211711).

    Gene: OGDH

    分子量

    116 kDa

    基因ID

    4967

    UniProt

    Q02218
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