OAZ3 抗体 (Internal Region)
Quick Overview for OAZ3 抗体 (Internal Region) (ABIN6263789)
抗原
See all OAZ3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- OAZ3 Antibody detects endogenous levels of total OAZ3.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human OAZ3, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Ornithine Decarboxylase Antizyme 3 (OAZ3) (AA 141-190) antibody
OAZ3 适用: 人, 小鼠, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 3 (OAZ3) (Middle Region) antibodyOAZ3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))
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别名
- OAZ3
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背景
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Description: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers. Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity (PubMed:17900240). Stabilizes AZIN2 by interfering with its ubiquitination. Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol. Probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells (By similarity).
Gene: OAZ3
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分子量
- 27 kDa
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基因ID
- 51686
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UniProt
- Q9UMX2
抗原
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