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Nth Endonuclease III-Like 1 (NTHL1) 抗体

This anti- antibody is a 兔 多克隆 antibody detecting in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN6263755
发货至: 中国

Quick Overview for Nth Endonuclease III-Like 1 (NTHL1) 抗体 (ABIN6263755)

抗原

See all Nth Endonuclease III-Like 1 (NTHL1) 抗体
Nth Endonuclease III-Like 1 (NTHL1)

适用

  • 35
  • 6
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 39
  • 2

克隆类型

  • 35
  • 6
多克隆

标记

  • 26
  • 7
  • 4
  • 2
  • 1
  • 1
非结合性

应用范围

  • 31
  • 26
  • 9
  • 7
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 特异性

    NTHL1 Antibody detects endogenous levels of total NTHL1

    交叉反应

    人, 小鼠

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human NTHL1

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C.Stable for 12 months from date of receipt

    有效期

    12 months
  • 抗原

    Nth Endonuclease III-Like 1 (NTHL1)

    别名

    NTHL1

    背景

    Description: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.

    Gene: NTHL1

    分子量

    34 kDa

    基因ID

    4913

    UniProt

    P78549
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