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GRIN2B 抗体 (C-Term)

Name: GRIN2B 抗体 (C-Term)
SKU: ABIN6263669
Availability: OutOfStock

This anti-GRIN2B antibody is a 兔多克隆 antibody detecting GRIN2B in WB, IHC, ELISA, IF 和 ICC. Suitable for 人, 大鼠和小鼠. This Primary Antibody has been cited in 1 publication.

Western blot analysis of NMDAR2B expression in A549 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. (GRIN2B 抗体 (C-Term))

IF/ICC

2 images

(1 reference)

产品编号 ABIN6263669

发货至: 中国

Datasheet as PDF

Quick Overview for GRIN2B 抗体 (C-Term) (ABIN6263669)

抗原

See all GRIN2B 抗体

GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

适用

人, 大鼠, 小鼠

宿主

兔

克隆类型

多克隆

标记

This GRIN2B antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Discover our top product GRIN2B Primary Antibody

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C-Term

特异性

NMDAR2B Antibody detects endogenous levels of total NMDAR2B.

预测反应

Pig,Bovine,Horse,Rabbit,Dog,Xenopus

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human NMDAR2B, corresponding to a region within C-terminal amino acids.

亚型

IgG
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (HRP)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 HRP

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (FITC)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 FITC

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Biotin)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 Biotin

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (PE)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 PE

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (APC)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 APC

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (PerCP)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 PerCP

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Atto 594)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 Atto 594

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Atto 488)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 Atto 488

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Atto 390)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 Atto 390

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 27-163) antibody
GRIN2B 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6E9A8 unconjugated

应用备注

WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
Sun, Xu, Yi, Chen, Wu, Cao, Zhou, Jiang, Zhang: "Role of 5-HT1A receptor in insular cortex mediating stress - induced visceral sensory dysfunction." in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, Vol. 28, Issue 7, pp. 1104-13, (2018) (PubMed).
抗原

GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

别名

GRIN2B

背景

Description: Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+ (PubMed:8768735, PubMed:26919761, PubMed:26875626, PubMed:28126851). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:8768735, PubMed:26875626). In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death. Contributes to neural pattern formation in the developing brain. Plays a role in long-term depression (LTD) of hippocampus membrane currents and in synaptic plasticity (By similarity).
Gene: GRIN2B

分子量

140kDa

基因ID

2904

UniProt

Q13224

途径

Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity