Neurexin 1 抗体 (N-Term)
Quick Overview for Neurexin 1 抗体 (N-Term) (ABIN6263607)
抗原
See all Neurexin 1 (NRXN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Neurexin I Antibody detects endogenous levels of total Neurexin I.
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预测反应
- Bovine
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Neurexin I, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Neurexin 1 (NRXN1) (AA 184-363) antibody
NRXN1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neurexin 1 (NRXN1) (C-Term) antibodyVerified NRXN1 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Neurexin 1 (NRXN1) (AA 31-130) antibodyNRXN1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Neurexin 1 (NRXN1) (AA 31-130) antibodyNRXN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4F7 unconjugated
anti-Neurexin 1 (NRXN1) (AA 31-310) antibodyNRXN1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurexin 1 (NRXN1) (AA 31-310) antibodyNRXN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neurexin 1 (NRXN1) (AA 77-110), (N-Term) antibodyNRXN1 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal RB52794 unconjugated
anti-Neurexin 1 (NRXN1) (AA 1328-1421) antibodyNRXN1 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Neurexin 1 (NRXN1) (AA 546-560), (Extracellular) antibodyNRXN1 适用: 大鼠 WB, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Neurexin 1 (NRXN1)
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别名
- NRXN1
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背景
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Description: Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca2+-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca2+-triggered exocytosis of secretory granules in pituitary gland. They may effect their functions at synapses and in endocrine cells via their interactions with proteins from the exocytotic machinery. Likewise, alpha-type isoforms play a role in regulating the activity of postsynaptic NMDA receptors, a subtype of glutamate-gated ion channels. Both alpha-type and beta-type isoforms may play a role in the formation or maintenance of synaptic junctions via their calcium-dependent interactions (via the extracellular domains) with neuroligin family members, CBLN1 or CBLN2. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Alpha-type isoforms were first identified as receptors for alpha-latrotoxin from spider venom (By similarity).
Gene: NRXN1
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分子量
- 150kDa
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基因ID
- 9378
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UniProt
- Q9ULB1
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途径
- Synaptic Membrane, Skeletal Muscle Fiber Development
抗原
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