Norrie Disease (Pseudoglioma) 抗体
Quick Overview for Norrie Disease (Pseudoglioma) 抗体 (ABIN6263552)
抗原
See all Norrie Disease (Pseudoglioma) (NDP) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- NDP Antibody detects endogenous levels of total NDP
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human NDP
-
亚型
- IgG
-
-
anti-Norrie Disease (Pseudoglioma) (NDP) (AA 25-133) antibody
NDP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Norrie Disease (Pseudoglioma) (NDP) (AA 25-133) antibodyNDP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Norrie Disease (Pseudoglioma) (NDP) (AA 1-133) antibodyNDP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Norrie Disease (Pseudoglioma) (NDP) antibodyNDP 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Norrie Disease (Pseudoglioma) (NDP) (Middle Region) antibodyNDP 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Norrie Disease (Pseudoglioma) (NDP) (N-Term) antibodyNDP 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-1:2000 IHC 1:50-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
-
有效期
- 12 months
-
-
- Norrie Disease (Pseudoglioma) (NDP)
-
别名
- NDP
-
背景
-
Description: Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. Acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). May be involved in a pathway that regulates neural cell differentiation and proliferation. Possible role in neuroectodermal cell-cell interaction.
Gene: NDP
-
分子量
- 15kDa
-
基因ID
- 4693
-
UniProt
- Q00604
-
途径
- Sensory Perception of Sound
抗原
-
