NDC80 抗体 (C-Term)
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- 抗原 See all NDC80 抗体
- NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NDC80 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- NDC80 Antibody detects endogenous levels of total NDC80.
- 预测反应
- Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human NDC80, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NDC80 Primary Antibody
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anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 545-642) antibody
NDC80 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A10 unconjugated
anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (C-Term) antibodyVerified NDC80 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 594-628) antibodyNDC80 适用: 人 WB 宿主: 兔 Polyclonal RB53951 unconjugated
anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 508-539) antibodyNDC80 适用: 人 WB 宿主: 兔 Polyclonal RB55345 unconjugated
anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 1-642) antibodyNDC80 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 1-642) antibodyNDC80 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 343-642) antibodyNDC80 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 351-400) antibodyNDC80 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))
- 别名
- NDC80 (NDC80 产品)
- 别名
- CG9938 antibody, Dmel\\CG9938 antibody, Hec1 antibody, NDC80 antibody, dNdc80 antibody, dmNdc80 antibody, hec1 antibody, KNTC2 antibody, ndc10 antibody, tid3 antibody, 2610020P18Rik antibody, AV139730 antibody, HEC antibody, HEC1 antibody, Kntc2 antibody, kntc2l antibody, wu:fb52e02 antibody, zgc:111801 antibody, HsHec1 antibody, TID3 antibody, hsNDC80 antibody, kntc2 antibody, NDC80, kinetochore complex component antibody, CG9938 gene product from transcript CG9938-RA antibody, spindle pole body protein Ndc80 antibody, kinetochore protein Ndc80 antibody, NDC80 homolog, kinetochore complex component (S. cerevisiae) antibody, NDC80 kinetochore complex component antibody, NDC80 kinetochore complex component S homeolog antibody, NDC80 antibody, Ndc80 antibody, ndc80 antibody, ndc80.S antibody
- 背景
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Description: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020). Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules (PubMed:25743205, PubMed:23891108).
Gene: NDC80
- 分子量
- 74kDa
- 基因ID
- 10403
- UniProt
- O14777
- 途径
- Maintenance of Protein Location
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