NDC80 抗体 (C-Term)
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北京 101111
Quick Overview for NDC80 抗体 (C-Term) (ABIN6263548)
抗原
See all NDC80 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- NDC80 Antibody detects endogenous levels of total NDC80.
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预测反应
- Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human NDC80, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 545-642) antibody
NDC80 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A10 unconjugated
anti-NDC80 Kinetochore Complex Component Homolog (NDC80) antibodyNDC80 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB415 unconjugated Recombinant Antibody
anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (C-Term) antibodyVerified NDC80 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-NDC80 Kinetochore Complex Component Homolog (NDC80) antibodyNDC80 适用: 人 WB, ICC, DB 宿主: 小鼠 Monoclonal 2497C3a unconjugated
anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (Internal Region) antibodyNDC80 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 343-642) antibodyNDC80 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 1-249) antibodyNDC80 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NDC80 Kinetochore Complex Component Homolog (NDC80) antibodyNDC80 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 508-539) antibodyNDC80 适用: 人 WB 宿主: 兔 Polyclonal RB55345 unconjugated
anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 594-628) antibodyNDC80 适用: 人 WB 宿主: 兔 Polyclonal RB53951 unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))
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别名
- NDC80
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背景
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Description: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020). Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules (PubMed:25743205, PubMed:23891108).
Gene: NDC80
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分子量
- 74kDa
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基因ID
- 10403
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UniProt
- O14777
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途径
- Maintenance of Protein Location
抗原
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