NAT10 抗体 (Internal Region)
Quick Overview for NAT10 抗体 (Internal Region) (ABIN6263520)
抗原
See all NAT10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- NAT10 Antibody detects endogenous levels of total NAT10.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human NAT10, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-N-Acetyltransferase 10 (GCN5-Related) (NAT10) antibody
NAT10 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-N-Acetyltransferase 10 (GCN5-Related) (NAT10) antibodyNAT10 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-N-Acetyltransferase 10 (GCN5-Related) (NAT10) (AA 146-178) antibodyNAT10 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB57638 unconjugated
anti-N-Acetyltransferase 10 (GCN5-Related) (NAT10) (AA 1-250) antibodyNAT10 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Acetyltransferase 10 (GCN5-Related) (NAT10) (AA 2-98) antibodyNAT10 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-N-Acetyltransferase 10 (GCN5-Related) (NAT10) (Internal Region) antibodyVerified NAT10 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- NAT10 (N-Acetyltransferase 10 (GCN5-Related) (NAT10))
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别名
- NAT10
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背景
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Description: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs (PubMed:25411247, PubMed:25653167). Catalyzes the formation of N4-acetylcytidine (ac4C) at position 1842 in 18S rRNA (PubMed:25411247). May also catalyze the formation of ac4C at position 1337 in 18S rRNA (By similarity). Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis (PubMed:25411247, PubMed:25653167). Catalyzes the formation of ac4C in serine and leucine tRNAs (By similarity). Requires the tRNA-binding adapter protein THUMBD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation (PubMed:25653167). Can acetylate both histones and microtubules (PubMed:14592445, PubMed:17631499, PubMed:19303003). Histone acetylation may regulate transcription and mitotic chromosome de-condensation (PubMed:17631499). Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization (PubMed:14592445, PubMed:18082603). Acetylates alpha-tubulin, which may affect microtubule stability and cell division (PubMed:19303003).
Gene: NAT10
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分子量
- 116 kDa
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基因ID
- 55226
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UniProt
- Q9H0A0
抗原
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