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MTM1 抗体 (C-Term)

This 兔 多克隆 anti-MTM1 antibody specifically detects MTM1 in WB, ELISA 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6263422
发货至: 中国
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Quick Overview for MTM1 抗体 (C-Term) (ABIN6263422)

抗原

See all MTM1 抗体
MTM1 (Myotubularin 1 (MTM1))

适用

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人, 小鼠, 大鼠

宿主

  • 42
  • 5
  • 1

克隆类型

  • 44
  • 4
多克隆

标记

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This MTM1 antibody is un-conjugated

应用范围

  • 41
  • 14
  • 14
  • 13
  • 6
  • 5
  • 2
  • 2
  • 1
  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 16
    • 8
    • 3
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    • 1
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    C-Term

    特异性

    MTM1 Antibody detects endogenous levels of total MTM1.

    预测反应

    Pig,Bovine,Horse,Rabbit,Dog,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human MTM1, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    MTM1 (Myotubularin 1 (MTM1))

    别名

    MTM1

    背景

    Description: Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.

    Gene: MTM1

    分子量

    70kDa

    基因ID

    4534

    UniProt

    Q13496

    途径

    Inositol Metabolic Process, Skeletal Muscle Fiber Development
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