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MLKL 抗体 (Internal Region)

Name: MLKL 抗体 (Internal Region)
SKU: ABIN6263279
Availability: OutOfStock

This anti-MLKL antibody is a 兔多克隆 antibody detecting MLKL in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 1 publication.

Western blot analysis of extracts of THP-1 , using MLKL antibody. (MLKL 抗体 (Internal Region))

IF/ICC

ABIN6277654 at 1/100 staining Human liver cancer tissue by IHC-P. (MLKL 抗体 (Internal Region))

IHC

3 images

(1 reference)

产品编号 ABIN6263279

发货至: 中国

Quick Overview for MLKL 抗体 (Internal Region) (ABIN6263279)

抗原

See all MLKL 抗体

MLKL (Mixed Lineage Kinase Domain-Like (MLKL))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This MLKL antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Discover our top product MLKL Primary Antibody

抗原表位
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Internal Region

特异性

MLKL Antibody detects endogenous levels of total MLKL.

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human MLKL, corresponding to a region within the internal amino acids.

亚型

IgG
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 371-471) antibody
MLKL 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3B2 unconjugated

anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 444-472) antibody
MLKL 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 1-471) antibody
MLKL 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Mixed Lineage Kinase Domain-Like (MLKL) (pSer358) antibody
MLKL 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal 6E3 unconjugated

anti-Mixed Lineage Kinase Domain-Like (MLKL) antibody
MLKL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Mixed Lineage Kinase Domain-Like (MLKL) antibody
MLKL 适用: 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mixed Lineage Kinase Domain-Like (MLKL) antibody
MLKL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 444-472), (C-Term) antibody
MLKL 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Mixed Lineage Kinase Domain-Like (MLKL) (N-Term) antibody
MLKL 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 1-471) antibody
MLKL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
Fang, Cao, Wang, Ye, Shen, Li, Hu, Gao: "Alterations in necroptosis during ALDH2‑mediated protection against high glucose‑induced H9c2 cardiac cell injury." in: Molecular medicine reports, Vol. 18, Issue 3, pp. 2807-2815, (2018) (PubMed).
抗原

MLKL (Mixed Lineage Kinase Domain-Like (MLKL))

别名

MLKL

背景

Description: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Gene: MLKL

分子量

54kDa

基因ID

197259

UniProt

Q8NB16