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MAP4K6 抗体 (Internal Region)

This 兔 多克隆 antibody specifically detects MAP4K6 in WB, ELISA, ICC 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN6263255
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MAP4K6 抗体 (Internal Region) (ABIN6263255)

抗原

See all MAP4K6 (MINK1) 抗体
MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))

适用

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宿主

  • 30

克隆类型

  • 30
多克隆

标记

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This MAP4K6 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

    • 8
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    • 1
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    Internal Region

    特异性

    MINK1 Antibody detects endogenous levels of total MINK1.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Dog,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human MINK1, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))

    别名

    MINK1

    背景

    Description: Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1.

    Gene: MINK1

    分子量

    150kDa

    基因ID

    50488

    UniProt

    Q8N4C8

    途径

    Synaptic Membrane
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